THERAPEUTIC INDEX DIGOXIN

Index. NA+/K+-ATPase and inhibitors (Digoxin) . The essential therapeutic use of digoxin which is more used than digitoxin is the treatment of cardiac .

Drug interactions with digoxin are important because of this agent's narrow therapeutic index. Among the drugs that can decrease digoxin bioavailability are .

Potentially defective digoxin tablets have been recalled by generic drug maker . it has a narrow therapeutic index and the existence of a higher than .

Digitalis leaf has a narrow therapeutic index, requiring close medical supervision for safe use. Traditional dosage starts at 1.5 g of leaf divided into 2 .

The drug has a narrow therapeutic index and the existence of higher than labeled dose may pose a risk of digoxin toxicity in patients with renal failure. .

13 May 2009 . Digoxin has a narrow therapeutic index and a small increase in dose can result in digoxin toxicity with symptoms of nausea, vomiting, .

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What is the therapeutic index for Lanoxin? Is there a graph for therapeutic index? What is the therapeutic index of digoxin? What is the therapeutic index .

The therapeutic index for diazepam is somewhat forgiving at about 100. Other drugs, however, are much less so, such as Digoxin, with an index of 2 or 3. .

Digoxin has a narrow therapeutic index. Therefore, therapeutic drug monitoring is essential for achieving optimal efficacy as well as for avoiding toxicity. .


Therapeutic Index Digoxin Therapeutic Index Digoxin

15 Oct 2008 . Because of this narrow therapeutic index, adverse drug reactions are common. It has been common practice to check digoxin levels by taking .

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. as narrow therapeutic index, difficult to define therapeutic endpoints, . of digoxin required to maintain the concentration in the therapeutic range. .

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. hospital setting that may compete for common hepatic enzymes (acetaminophen or lidocaine) or that have a low therapeutic index (lidocaine or digoxin). .

by TE Jones - 2008 - Cited by 3 - Related articles

Others believe that digoxin may be used in these patients if adequate serum level . Because of this drug's narrow therapeutic index, and interpatient .

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12 Feb 2011 . digoxin therapeutic index chronic atrial fibrillation digoxin mechanism of action atrial fibrillation digoxin and solubility .


Therapeutic Index Digoxin Therapeutic Index Digoxin

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Patients taking drugs with a narrow therapeutic index such as digoxin should be discouraged from using herbal products. All drugs with a narrow therapeutic .

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8 Jan 2008 . Digoxin is a form of digitalis, a drug that is extracted from the leaves of the foxglove . and is described as a narrow therapeutic index. .

by E Zalzstein - 2003 - Cited by 1 - Related articles

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This applies to all agents, not just medications with a narrow therapeutic index such as digoxin, warfarin,. Is this medicine really involved in a drug .


Therapeutic Index Digoxin Therapeutic Index Digoxin

6 Oct 2010 . Digoxin is a drug that is commonly used to treat congestive heart failure. Because of digoxin's narrow therapeutic index, patients are .

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However, owing to its narrow therapeutic index, interactions that alter the digoxin AUC > 1.25-fold are clinically important for digoxin. .

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1 Apr 2009 . The drug has a narrow therapeutic index and the existence of higher than labeled dose may pose a risk of digoxin toxicity in patients with .

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Two of the most prominent features of the clinical use of digoxin are its narrow therapeutic index and an endpoint of therapy which is difficult to define .

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Therapeutic Index Digoxin Therapeutic Index Digoxin

Therapeutic drug monitoring refers to the individualisation of dosage by . narrow therapeutic index; defined therapeutic (target) concentration range . . While the digoxin therapeutic range is somewhat 'loose', the advent of .

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1 post - Last post: 20 Febdrug monitoring digoxin therapeutic index digoxin antacid aluminum hydroxide digoxin in nursing metformin and digoxin diovan .

The therapeutic index (also known as therapeutic ratio), is a comparison of the . to achieve therapeutic levels and minimise toxicity, include: digoxin, .

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Despite being widely prescribed, acute overdosage with digoxin is uncommon. However, digoxin has a low therapeutic index and toxicity is common. .

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26 Apr 2010 . Digoxin has a narrow therapeutic index (the margin between effectiveness and toxicity). Therapeutic serum digoxin concentrations is between .

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Even though digoxin has a very narrow therapeutic index, it remains an important therapeutic strategy when added to standard therapy. When used in HF, .

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Dr. Rattazzi's digoxin level is above the usual therapeutic index, confirming your suspicion of digitalis toxicity (which can occur even in the presence of .

1 Apr 2009 . The drug has a narrow therapeutic index and the existence of higher than labeled dose may pose a risk of digoxin toxicity in patients with .

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4 Nov 2005 . digoxin lanoxin, narrow therapeutic index, apical pulse: Hi,Michelle! Since digoxin is a medication with a narrow therapeutic index, .

13 May 2009 . Digoxin is a drug product used to treat heart failure and abnormal heart rhythms . It has a narrow therapeutic index and the existence of .

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26 Jun 2010 . The therapeutic index of Digoxin is rather small which means that even the slightest alteration in the dosage or the blood level of the drug .

8 Dec 2010 . Digoxin has a narrow therapeutic index, which means that small variations in tablet potency could have serious effects. .

5 May 2009 . (1,2) While digoxin therapy does offer a number of therapeutic . In addition, it is a narrow therapeutic index medication and thus .

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Digoxin kinetics in http://digoxin.gagand.com digoxin. side effects of digoxin . digoxin dog supplement digoxin therapeutic index. digoxin toxicity%2C .

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Latest Recalls Tagged as Narrow Therapeutic Index. AS Medications Solution LLC. Announces a Nationwide Recall of All Lots of Digoxin Tablets 0.25mg Due to .

Alternatives to Digoxin. Manufacturing defects in Digitek and Caraco brand digoxin . Because of their narrow therapeutic index, taking too little of the .

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Therapeutic Index Digoxin Therapeutic Index Digoxin

The therapeutic index of vitamin D analogs is narrow, and there is great . Digoxin: Vitamin D should be used with caution in patients on digoxin as .

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Bioavailability of digoxin dose forms varies considerably (relative to the therapeutic index). Patient monitoring should be increased when a change is made . .

26 Jan 2011 . Narrow therapeutic index drugs. The list below mentions some examples of narrow therapeutic index drugs: Warfarin; Lithium; Digoxin .

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Digoxin has a very low therapeutic index of 1-2 mcg/l with a toxic dose being between 2-9mcg/l and an ineffective dose of <1 (Oh 1997, p. .

31 Mar 2009 . The Digoxin medications have a very narrow therapeutic index, and receiving too much of the drug could cause digitalis toxicity, .

Digoxin preparations are commonly marketed under the trade names Lanoxin, .

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Digoxin has a narrow therapeutic index and medication-related toxicity is reported in as many as 5 to 23% of digoxin recipients.4 This narrow margin between .


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18 Nov 2010 . Because digoxin is subject to various drug-drug interactions and because it has a relatively narrow therapeutic index, the dosage should be .

20 Apr 2010 . Example: Lithium, phenytoin, digoxin. Patients who have impaired clearance of a drug with a narrow therapeutic index are candidates for drug .

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13 Apr 2005 . Digoxin - The low therapeutic index of digoxin means that dose adjustment must be performed with caution. Results can only be interpreted .

Like digitalis digoxin too has narrow therapeutic index, therefore must be taken exactly as prescribed. Side effects are: Most common are;. Nausea; Diarrhea .

Digoxin tablets and injection both contain the active ingredient digoxin, . is true of a few medicines, and is described as a narrow therapeutic index. .

(a) Where the drug has a narrow therapeutic index (eg. Digoxin, Aminoglycosides, Theophylline, Anticonvulsants). (b) Where the pharmacological effect is .